2,689 results found
    1. Neuroscience

    Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation

    Elizabeth C Marin, Billy J Morris ... Gregory SXE Jefferis
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Strategically managing learning during perceptual decision making

    Javier Masís, Travis Chapman ... Andrew M Saxe
    During perceptual decision making, maximizing total reward in the long term requires trading reward in the short term for a faster improvement in perceptual representations.
    1. Computational and Systems Biology
    2. Neuroscience

    Microsaccadic sampling of moving image information provides Drosophila hyperacute vision

    Mikko Juusola, An Dau ... Jouni Takalo
    New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.
    1. Neuroscience

    Multiple decisions about one object involve parallel sensory acquisition but time-multiplexed evidence incorporation

    Yul HR Kang, Anne Löffler ... Michael N Shadlen
    When making two decisions about one object, two streams of information can be acquired in parallel but must be incorporated into the two decisions serially, consistent with a central bottleneck.
    1. Computational and Systems Biology
    2. Neuroscience

    A connectome and analysis of the adult Drosophila central brain

    Louis K Scheffer, C Shan Xu ... Stephen M Plaza
    New reconstruction methods are used to create a publicly available dense reconstruction of the neurons and chemical synapses of central brain of Drosophila, with analysis of its graph properties.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

    Olivier Cochet-Escartin, Mete Demircigil ... Jean-Paul Rieu
    Cell assemblies can use environmental cues created by their own respiration, such as oxygen gradients, to collectively guide themselves to more favorable locations in a remarkably robust and long-lasting way.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

    Eitan Lerner, Anders Barth ... Shimon Weiss
    A summary of the current “state-of-the-field” of single-molecule FRET used for probing biomolecular structural dynamics.
    1. Neuroscience

    Chemoreceptor co-expression in Drosophila melanogaster olfactory neurons

    Darya Task, Chun-Chieh Lin ... Christopher J Potter
    Olfactory neurons of insects, once thought to express only a single type of olfactory receptor, exhibit widespread co-expression of receptors from multiple chemosensory gene families.
    1. Evolutionary Biology

    Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

    Fabien Duveau, Andrea Hodgins-Davis ... Patricia J Wittkopp
    The impact of changing gene expression noise on fitness reveals beneficial or deleterious effects in a stable environment depending how close the average expression level is to the fitness optimum.
    1. Evolutionary Biology

    Fitness variation across subtle environmental perturbations reveals local modularity and global pleiotropy of adaptation

    Grant Kinsler, Kerry Geiler-Samerotte, Dmitri A Petrov
    A set of adaptive mutations affect only a small number of phenotypes that matter in the evolution condition, and yet contain substantial latent functional diversity revealed in distant environments.

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