Debashish Bhattacharya, Shobhit Agrawal ... Paul G Falkowski
The analysis of 20 coral genomic datasets provides unprecedented insights into what makes reef-building corals unique, including the evolution of novel gene families involved in biomineralization, signaling and stress responses that have led to their evolutionary success throughout the Phanerozoic Eon.
Bruno Popik, Felippe Espinelli Amorim ... Lucas De Oliveira Alvares
Deconditioning is a safe and efficient new approach to updating traumatic memories, in which fear memory is rewritten to a very low level in a long-lasting way.
Laurie Peverini, Sophie Shi ... Pierre-Jean Corringer
Conformational motions elicited by antagonists, partial agonists, and agonists in serotonin-gated ion channels 5-HT3AR progressively spread from the extracellular to the transmembrane domain.
Jean-Emmanuel Hugonnet, Dominique Mengin-Lecreulx ... Michel Arthur
Production of the L,D-transpeptidase YcbB and elevated synthesis of the (p)ppGpp alarmone reveals a new mode of peptidoglycan polymerization that bypasses the D,D-transpeptidase activity of PBPs and leads to broad-spectrum β-lactam resistance in Escherichia coli.
Grace E Hamilton, Luke A Helgeson ... Trisha N Davis
Two components of the inner kinetochore (OA and Mif2) are independently capable of transmitting physiologically relevant forces to a centromeric nucleosome.
The first example of an animal where RNA-editing dramatically reshapes the entire proteome demonstrates that editing must be a critical evolutionary and adaptive force.
Karla J Suchacki, Benjamin J Thomas ... William P Cawthorn
The health benefits of caloric restriction, including decreasing body fat and blood glucose, differ between males and females and this difference depends on the age at which caloric restriction begins.
Ximena Ibarra-Soria, Thiago S Nakahara ... Darren W Logan
The neuronal composition of a mouse’s nose is individually unique due to a combination of olfactory experience and genetic variation local to olfactory receptor genes.