2,289 results found
    1. Cancer Biology
    Reproducibility Project

    Reproducibility Project: Cancer Biology

    Edited by Roger J Davis et al.
    Investigating reproducibility in preclinical cancer research.
  1. Episode 57: May 2019

    In this episode, we hear about a 99 million-year-old beetle, the consequences of early-life inflammation, malaria's DNA passport, redesigning images in biology and Mike Eisen's vision for science.
  2. Episode 45: February 2018

    In this episode, we hear about disease control in insects, placental development, post-traumatic stress disorder, the mission to create a human cell atlas and how crickets amplify their song.
    1. Neuroscience

    Distinct roles for innexin gap junctions and hemichannels in mechanosensation

    Denise S Walker, William R Schafer
    The innexin protein UNC-7, a homologue of vertebrate pannexins, plays a specific, gap junction-independent role in C. elegans mechanosensation.
    1. Structural Biology and Molecular Biophysics

    Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175

    SeCheol Oh et al.
    Structures of the non-canonical potassium channel TMEM175 in open and closed states reveal unique mechanisms for channel gating and the selective permeation of K+ ions.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The guide sRNA sequence determines the activity level of box C/D RNPs

    Andrea Graziadei et al.
    Integrative structural biology reveals a conformational equilibrium in the Box C/D methylation enzyme that regulates the extent of site-specific 2'-O-rRNA methylation in dependence of the RNA sequence.
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Homologue replacement in the import motor of the mitochondrial inner membrane of trypanosomes

    Corinne von Känel et al.
    Mitochondrial inner membrane translocation of presequence-containing proteins by the single bifunctional TIM complex of T. brucei requires an non-canonical J domain-containing protein.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages

    Jay Lubow et al.
    Interactions between HIV-1 Env and human mannose receptor enhance HIV entry but restrict viral egress and spread in the absence of Vpr.
    1. Cancer Biology
    2. Cell Biology

    Junction Mapper is a novel computer vision tool to decipher cell–cell contact phenotypes

    Helena Brezovjakova et al.
    Junction Mapper is a powerful new semi-automated software that provides a fingerprint of cell–cell contact morphometry and receptor density alterations.
    1. Cell Biology
    2. Developmental Biology

    The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in C. elegans and in human cells

    Andrea Haag et al.
    The co-chaperone CHORDC1 is specifically required for epidermal growth factor receptor trafficking and signaling in Caenorhabditis elegans and in human cells.

Refine your results by:

Type
Research categories