539 results found
    1. Neuroscience

    Controllability boosts neural and cognitive signatures of changes-of-mind in uncertain environments

    Marion Rouault, Aurélien Weiss ... Valentin Wyart
    Task controllability manipulations reveal that information seeking is associated with reduced confidence and active hypothesis testing, as well as stronger neurophysiological correlates of attention and arousal.
    1. Physics of Living Systems

    Active morphogenesis of patterned epithelial shells

    Diana Khoromskaia, Guillaume Salbreux
    An epithelium modelled as an active, nematic surface can display flattening, budding, and tubulation morphogenetic events, which are observed during development in biological organisms.
    1. Neuroscience

    The normalization model predicts responses in the human visual cortex during object-based attention

    Narges Doostani, Gholam-Ali Hossein-Zadeh, Maryam Vaziri-Pashkam
    A normalization model is shown to predict responses to multiple objects across changes in the attentional state in the visual cortex, providing evidence for the role of normalization as a fundamental operation in the human brain.
    1. Developmental Biology
    2. Genetics and Genomics

    Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling

    Gang Zhai, Tingting Shu ... Zhan Yin
    Augmentation of progestin signaling promotes testis development and spermatogenesis independent from andorgen signaling in zebrafish.
    1. Neuroscience

    Toward a more informative representation of the fetal–neonatal brain connectome using variational autoencoder

    Jung-Hoon Kim, Josepheen De Asis-Cruz ... Catherine Limperopoulos
    A nonlinear deep generative model can represent fetal–neonatal resting-state functional magnetic resonance imaging better than conventional linear models.
    1. Genetics and Genomics

    Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations

    M Elise Lauterbur, Maria Izabel A Cavassim ... Ilan Gronau
    Stdpopsim, a framework for generating realistic chromosome-scale simulations, is expanded to facilitate simulations for non-model species, resulting in insights into how such simulations should be designed.
    1. Neuroscience

    Sleep spindle maturity promotes slow oscillation-spindle coupling across child and adolescent development

    Ann-Kathrin Joechner, Michael A Hahn ... Markus Werkle-Bergner
    Across four samples of children, adolescents, and young adults, age-related higher similarity of dominant, development-specific fast sleep spindles and adult-like fast sleep spindles is uniquely related to stronger and more precise slow oscillation-sleep spindle coupling.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

    Amy R Strom, Ronald J Biggs ... Andrew D Stephens
    Micromanipulation experiments demonstrate that HP1α strengthens interphase and mitotic chromosome mechanics and maintains nuclear shape by chromatin crosslinking, separate from histone methylation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High social status males experience accelerated epigenetic aging in wild baboons

    Jordan A Anderson, Rachel A Johnston ... Jenny Tung
    Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.
    1. Evolutionary Biology

    A Bayesian approach to dynamic homology of morphological characters and the ancestral phenotype of jawed vertebrates

    Benedict King, Martin Rücklin
    The ancestor of all known jawed vertebrates possessed a maxilla and premaxilla and was similar in morphology to the 'maxillate placoderms' from China.

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