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    1. Chromosomes and Gene Expression

    Ubiquitination-dependent control of sexual differentiation in fission yeast

    Fabrizio Simonetti et al.
    The RNA-binding protein Mmi1 targets its own inhibitor Mei2 for ubiquitination by the E3 ubiquitin ligase Not4/Mot2 in order to preserve its role in meiotic mRNA decay during vegetative growth.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Eighteenth century Yersinia pestis genomes reveal the long-term persistence of an historical plague focus

    Kirsten I Bos et al.
    The analysis of 18th century Y. pestis genomes reveals a bacterial lineage that might be responsible for the 400-year period of European plague epidemics from the Renaissance through early modern times.
  1. Living Science: Grandmother elephants

    Eve Marder
    As new technology makes it possible to perform experiments that were unimaginable a decade ago, Eve Marder argues that we can still learn from the past.
  2. Meta-Research: How significant are the public dimensions of faculty work in review, promotion and tenure documents?

    Juan P Alperin et al.
    An analysis of review, promotion and tenure documents from 129 US and Canadian universities suggests institutions could better fulfill their public missions by changing how they incentivize the public dimensions of faculty work.