Using self-organization, cells can collectively leverage defects in nematic and hexatic orders to localize mechanical stresses and remove an unwanted cell with their preferred path to achieve this explored here by independently tuning cell–cell and cell–substrate adhesion strengths.

A novel family of nucleolus-enriched ncRNAs forms allele-specific territories on the nucleolar organizing region (NOR)-containing acrocentric chromosomes.

An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.

Single-cell transcriptomes of larval zebrafish whole brain shed light on the multidimensional landscapes of transcription factors and post-transcriptional regulators in vertebrate whole-brain neuronal classification and revealed principles of how neuronal cell diversity develops and evolves.

Comprehensive investigation reveals the variability and importance of the nuclear pore complex in HIV-1 infection and the activity of the antiretroviral protein, MX2.

Active and passive contributions to cell shape change and rearrangements can be distinguished from observed cell geometry, revealing the self-organization mechanisms underlying internally-driven epithelial convergent extension.

The integrated quantification of spontaneous dynamic cell-cell force transmissions at both multi-cellular and subcellular scales enables spatiotemporal correlations of stress distribution with biomolecules in small cell clusters.

A microfluidic device induces doxorubicin-resistant polyaneuploid cancer cells from triple negative breast cancer cells, revealing NUPR1/HDAC11 axis dysfunction drives chemoresistance, increasing tumor heterogeneity and impacting clinical outcomes.