Nuria Martin Flores, Marina Podpolny ... Patricia C Salinas
The Wnt antagonist DKK3 is a key regulator of excitatory and inhibitory synapses, and its downregulation in the hippocampus restores synaptic connectivity and memory in an Alzheimer's disease mouse model.
Meghan Laturney, Gabriella R Sterne, Kristin Scott
Postmated increases in sucrose consumption in Drosophila melanogaster females is executed by a female specific circuit that alters neuroendocrine centers to promote hunger.
Yishan Sun, Sergiu P Paşca ... Ricardo E Dolmetsch
A human cellular model of a prototypical form of intractable childhood epilepsy supports selective impairment of inhibitory neurons as a key pathophysiological mechanism.
Justinn Barr, Maria Elena Gentile ... Andrew E Vaughan
Influenza-induced pulmonary tuft cells are a heterogenous population and emerge independently of Type 2 and interferon signaling, and do not impact dysplastic epithelial regeneration.
Purification of two conserved protein complexes, the γ-TuRC and Augmin, using a simple affinity technique, demonstrates that they are necessary and sufficient for the essential phenomenon of branching microtubule nucleation.