A new collection of fly strains comprehensively targets the motor neurons of the proboscis, allowing separate control of every muscle to determine how this appendage achieves flexible, directed reaching.

A fully blinded replication of the most convincing report of associative learning in plants failed to reproduce the phenomenon.

Unique 'true' S-cone and S-cone bipolar cell distribution patterns in the mouse retina are previously unappreciated anatomical features that support enhanced short-wavelength signaling for color detection above horizon.

Dorsal raphe Pet1 neurons are molecularly heterogeneous, comprising as many as fourteen distinct subtypes that show biased cell body distributions across dorsal raphe subdomains.

Identification of a two-tier functional redundancy to combat proteostasis imbalance induced due to tRNA expansion and oxidative stress in multicellular animals.

Genetic and molecular analyses show that FOXC1 and FOXC2 play a role in controlling lymphatic valve maintenance as key mediators of mechanotransduction to control cytoskeletal organization and RhoA/ROCK signaling.

By thinking about experimental techniques in terms of six broad approaches – perturbation, visualization, substitution, characterization, reconstitution, and simulation – researchers may be able to generate more reliable inferences.

The reduced ability of Drosophila imaginal discs to regenerate as they mature can be explained by the silencing of damage-responsive enhancers that regulate expression of genes required for regeneration.

Wnt/beta-catenin signaling is essential for the specification of dorsal cell fate in amphioxus, suggesting a common evolutionary origin for the formation of the dorsal organizer in chordates.