487 results found
  1. March 2015

    Episode 19: March 2015

    In this episode we hear about herpes, breweries, model organisms, social interactions in rats and traumatic brain injuries in flies.
  2. August 2016

    Episode 31: August 2016

    In this episode we hear about human height, fish joints, colour vision, chimpanzees using tools and open science.
    1. Chromosomes and Gene Expression

    Genomic DNA transposition induced by human PGBD5

    Anton G Henssen et al.
    The human PGBD5 gene encodes an active DNA transposase.
    1. Epidemiology and Global Health
    2. Human Biology and Medicine

    Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial

    Manoj M Lalu et al.
    A rigorous and transparent evaluation of mesenchymal stem cell therapy for sepsis suggests it may be efficacious, although the strength of these findings is tempered by threats to validity in the studies that were included.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis

    Blessy Paul et al.
    Chlamydia hijacks membrane trafficking proteins of the human host via the cytoplasmic domain of a secreted transmembrane protein.
    1. Stem Cells and Regenerative Medicine

    Lineage tracing of genome-edited alleles reveals high fidelity axolotl limb regeneration

    Grant Parker Flowers et al.
    CRISPR-based lineage tracing in the axolotl shows that regenerated limbs are composed of the same cell lineages in the same frequencies as those that gave rise to the original limb.
    1. Cell Biology

    Centriolar remodeling underlies basal body maturation during ciliogenesis in Caenorhabditis elegans

    Inna V Nechipurenko et al.
    Building on previous work (Doroquez et al., 2014), it is shown that the centriole core of the basal body degenerates, but the outer wall remodels to template the ciliary axoneme in a subset of C. elegans ciliated sensory neurons.
    1. Stem Cells and Regenerative Medicine

    Embryonic origin of adult stem cells required for tissue homeostasis and regeneration

    Erin L Davies et al.
    Anarchic, cycling piwi-1+ embryonic cells gives rise to neoblasts, pluripotent stemcells required for development of all organ systems during S. mediterranea embryogenesis, as well as the maintenance andregeneration of tissues during adulthood.
    1. Cell Biology

    Waves of actin and microtubule polymerization drive microtubule-based transport and neurite growth before single axon formation

    Amy M Winans et al.
    Waves of polymerizing actin work in concert with microtubule polymerization to lay down more microtubules tracks and transiently increase microtubule-based transport into the growing neurite.
    1. Developmental Biology

    An intrinsic cell cycle timer terminates limb bud outgrowth

    Joseph Pickering et al.
    Size control in limbs is an intrinsically determined process.

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