Burst activity can be described in all three signal domains and sensorimotor beta burst activity propagates along two axes either parallel or perpendicular to the central sulcus.

Imaging with electron microscopy and cryo-electron tomography reveals that competition between Cdc42 and Gic1 for the same subunit within septins controls the formation and breakdown of septin filaments.

A medaka mutant revealed that Wnt11 promotes formation of uniquely large protrusions from non-myogenic dorsal dermomyotome cells, which guide the epaxial myotome dorsally to achieve the coverage of the neural tube.

Lipids with a propensity to form nonbilayer structures must be present for the last step of membrane fusion to take place.

Bidirectional regulation of the chromatin modification H3K27me3 orchestrates programs of gene expression that underlie postmitotic stages of neuronal maturation.

The secreted sugar-binding protein galectin-8 causes osteoblasts to secrete factors that promote the differentiation of bone marrow cells into osteoclasts; targeting this protein could therefore potentially help treat diseases associated with excessive bone loss.

Pre-RC component Cdc6 is primed for origin licensing by phosphatases and Cdk1 inhibitor.

Rigorous assays of membrane fusion show that a distinct tethering step is required for lumenal compartment mixing in a manner that extends beyond simply increasing the amount of total trans-SNARE complex.

Sec17 is shown to have divergent effects on pre-fusion SNARE complex activity, depending on the state of SNARE zippering and HOPS, an SM-tether complex, controls the outcome of Sec17-SNARE engagement.