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    1. Ecology
    2. Epidemiology and Global Health

    Tracking zoonotic pathogens using blood-sucking flies as 'flying syringes'

    Paul-Yannick Bitome-Essono et al.
    A field study coupled with a molecular analysis demonstrates that using hematophagous flies as 'flying syringes' could be used to investigate blood-borne pathogen diversity in wild vertebrates and act as an early detection tool of zoonotic pathogens.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Comparative analysis of viral RNA signatures on different RIG-I-like receptors

    Raul Y Sanchez David et al.
    An experimental approach allowing characterization of viral RNA ligands recognized by RIG-I-like receptors during infection by any RNA viruses is established and validated.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization

    Zhong-Yu Liu et al.
    A conserved element in the flavivirus genomic 5′ terminus switches its conformation in response to long-range RNA interactions, and thereby regulates the dynamic recruitment of viral replicase for efficient viral RNA replication.
    1. Ecology
    2. Epidemiology and Global Health

    Using mobile phones as acoustic sensors for high-throughput mosquito surveillance

    Haripriya Mukundarajan et al.
    Mobile phones can accurately capture sound recordings from mosquito wingbeats with species-specific frequencies, together with metadata about the recording time, location and conditions, to enable rapid low-cost mosquito surveillance using a citizen-science approach.
    1. Genomics and Evolutionary Biology
    2. Microbiology and Infectious Disease

    Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals

    William E Diehl et al.
    Endogenous virus sequences in the genomes of modern mammals reveal the global spread of an ancient virus lineage, including frequent interspecies transmission, adaptation, and emergence spanning several million years of mammalian evolution
    1. Cell Biology
    2. Microbiology and Infectious Disease

    EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus

    Parikshit Bagchi et al.
    Biochemical and cell-based analyses reveal how a non-enveloped virus exploits the chaperone activity of an ER transmembrane protein to penetrate the ER membrane required for successful virus infection.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Evaluating probabilistic dengue risk forecasts from a prototype early warning system for Brazil

    Rachel Lowe et al.
    The evaluation of a dengue early warning system demonstrates its potential to assist dengue prevention and control up to three months ahead of future epidemics.
    1. Biochemistry and Chemical Biology
    2. Biophysics and Structural Biology

    Structural insights into the mechanism of the DEAH-box RNA helicase Prp43

    Marcel J Tauchert et al.
    The structural and functional analysis of the ATP-dependent RNA helicase Prp43 provides insights into the mechanisms of RNA binding and translocation, which could serve as paradigm for all DEAH-box proteins.
  1. Publishing scientific images using the IIIF

    The International Image Interoperability Framework (IIIF) makes the world’s image repositories interoperable and accessible.