Radhika A Varier, Theodora Sideri ... Folkert J van Werven
N6-methyladenosine (m6A) reader Pho92 is directed by Paf1C to meiotic mRNAs in an m6A-dependent and independent manner and promotes CCR4-NOT-mediated mRNA decay of m6A modified transcripts contingent on translation.
María Angélica Bravo Núñez, Ibrahim M Sabbarini ... Sarah E Zanders
The wtf meiotic drivers change the fitness landscape of meiosis in outcrossed Schizosaccharomyces pombe demonstrating that genetic parasites can favor the evolution of variants that disrupt meiotic fidelity.
Investigation of how cells rewire their transcriptional programs during transition from mitotic to meiotic cell fate reveals a two-pronged mechanism for inactivating a key mitotic transcription factor.
Environmental DNA from highly standardized leaf sample time series suggests no localized species losses, but biotic turnover and homogenization, as main drivers of forest insect decline.
Distributed cohesin rings flexibly tether the axial element structure of meiotic chromosomes to the underlying chromatin to readily accommodate ongoing transcription.
The mouse gene Ythdc2 exemplifies an evolutionarily ancient family of crucial regulators of the transition from germline stem cell divisions to meiosis.