526 results found
    1. Structural Biology and Molecular Biophysics

    Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

    Mia L Abramsson, Robin A Corey ... Michael Landreh
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    The Genomic Legacy of Aurochs hybridization in ancient and modern Iberian Cattle

    Torsten Günther, Jacob Chisausky ... Cristina Valdiosera
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Medicine
    2. Neuroscience

    CCR5 antagonists as neuroprotective and stroke recovery enhancing agents: a preclinical systematic review and meta-analysis

    Ayni Sharif, Matthew S Jeffers ... Manoj M Lalu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Adipocyte microRNA-802 promotes adipose tissue inflammation and insulin resistance by modulating macrophages in obesity

    Yue Yang, Bin Huang ... Fangfang Zhang
    Mir802 serves as a pivotal mediator facilitating communication between adipose tissue and macrophages through the activation of NF-KB signaling pathways.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Harnessing AlphaFold to reveal hERG channel conformational state secrets

    Khoa Ngo, Pei-Chi Yang ... Igor Vorobyov
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Activity-dependent synapse clustering underlies eye-specific competition in the developing retinogeniculate system

    Chenghang Zhang, Tarlan Vatan, Colenso M Speer
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone

    Assmaa ElSheikh, Camden M Driggers ... Show-Ling Shyng
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    It’s the Sound, not the Pulse: Peripheral Magnetic Stimulation Reduces Central Sensitization through Auditory Modulatory Effects

    Spencer S Abssy, Natalie R Osborne ... Massieh Moayedi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Chromosomes and Gene Expression

    The Smc5/6 complex counteracts R-loop formation at highly transcribed genes in cooperation with RNase H2

    Shamayita Roy, Hemanta Adhikary ... Damien D'Amours
    Genetic analyses in budding yeast coupled with biochemical assays have revealed an unexpected role for the Smc5/6 complex in cellular pathways responsible for the prevention of RNA formation in genomic DNA.
    1. Neuroscience

    Point of View: An annotated introductory reading list for neurodiversity

    Mirela Zaneva, Tao Coll-Martín ... Alyssa Hillary Zisk
    A collaboratively developed annotated reading list expands upon core themes in neurodiversity, aiming to enhance understanding and to promote rigorous, destigmatizing, and inclusive practices in research.

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