5,374 results found
  1. electrophysiological signals

    Python for the practicing neuroscientist: an online educational resource

    Learn to analyze neural data using Python with this interactive, case study-based approach
    1. Developmental Biology
    2. Immunology and Inflammation

    Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism

    Chew Leng Lim et al.
    Estrogen aggravates mammary involution through lysosome-mediated cell death, neutrophil recruitment via CXCR2 signalling, neutrophil-mediated inflammation and adipocyte repopulation.
    1. Developmental Biology
    2. Genetics and Genomics

    Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos

    Theodora Koromila et al.
    The gene Odd-paired is a late-acting regulator of zygotic gene expression, functioning coordinately with Zelda to influence chromatin accessibility and affecting genes expressed along both axes of Drosophila embryos.
    1. Cell Biology
    2. Immunology and Inflammation

    Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex

    Daniel Blumenthal et al.
    The dendritic cell actin cytoskeleton provides a platform for T cell mechanosensing, delivering novel biophysical cues that serve as costimulatory signals for T cell activation.
    1. Neuroscience

    Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination

    Cristina Blázquez et al.
    Δ9-Tetrahydrocannabinol impairs motor coordination in mice by inhibiting autophagy in the striatonigral pathway, thus defining a new conceptual view of how cannabis acts in the brain.
    1. Biochemistry and Chemical Biology

    Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation throughout mRNA lifespan with most impact on short tails

    Sandy Mattijssen et al.
    LARP4 protects mRNAs against deadenylation over a wide range of poly(A) lengths but with most apparent functional impact on short lengths known to sensitize PABP binding and mRNA stability.
    1. Neuroscience

    Different theta frameworks coexist in the rat hippocampus and are coordinated during memory-guided and novelty tasks

    Víctor J López-Madrona et al.
    Integration and segregation of information of memory and sensory in the hippocampus could be achieved by the coordination of distinct theta-gamma coding frameworks.
  2. Research Culture: Actionable recommendations from trainees to improve science training

    Stephanie M Davis et al.
    Early-career researchers propose seven actions that can be taken by research institutions and departments to improve science training.
    1. Neuroscience

    The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling

    Amy A Worth et al.
    The GDF15 receptor, GFRAL,is expressed on a unique population of brainstem CCK neurons and mediates pathophysiological anorexia.

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