Browse the search results

Page 2 of 3
    1. Evolutionary Biology

    The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions

    Alessandro W Rossoni et al.
    Horizontal gene transfer (HGT) analysis in polyextremophile red algae (Cyanidiales) provides explanations for the nonexistence of cumulative effects and eukaryotic pangenomes, and highlights differences between HGT and native genes.
    1. Biochemistry and Chemical Biology

    Mechanism of cargo-directed Atg8 conjugation during selective autophagy

    Dorotea Fracchiolla et al.
    Autophagic cargo receptors recruit the E3-like enzyme for Atg8 lipid conjugation to the cargo and thereby promote local formation of Atg8-positive autophagosomal membranes.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes

    Palaniraja Thandapani et al.
    Arginine methylation regulates mRNA translation of key protooncogenes via an RGG/RG motif-containing protein called Aven.
    1. Genetics and Genomics

    PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans

    Heesun Kim et al.
    PIE-1 engages SUMO to preserve the embryonic germline fate and also to promote the assembly of a MEP-1/Mi-2/HDA-1 chromatin remodeling complex required for inherited Argonaute-mediated gene silencing in the adult hermaphrodite germline.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans

    Gurmeet Kaur et al.
    Prokaryotic TRADD-N and Death-like adaptor domains in diverse predicted apoptosis and immune systems from multicellular prokaryotes and metazoans indicate the common origin of key apoptosis mechanisms required for the stabilization of multicellularity.
    1. Structural Biology and Molecular Biophysics

    Structure of the bacterial ribosome at 2 Å resolution

    Zoe L Watson et al.
    High-resolution maps and models of the bacterial ribosome provide new chemical insights into protein synthesis, and should enable the development of robust tools for cryo-EM structure modeling and refinement.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase

    Gulzhan Raiymbek et al.
    A putative histone demethylase in fission yeast has non-enzymatic properties that regulates heterochromatin assembly and epigenetic inheritance.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Adaptation to mutational inactivation of an essential gene converges to an accessible suboptimal fitness peak

    João V Rodrigues, Eugene I Shakhnovich
    When an essential metabolic gene in E. coli is mutationally inactivated, subsequent evolution rarely reverts the mutation to wild type but rather follows unexpected paths that rewire metabolic fluxes.
    1. Chromosomes and Gene Expression

    Telomere repeats induce domains of H3K27 methylation in Neurospora

    Kirsty Jamieson et al.
    Vast regions of facultative heterochromatin marked by methylation of lysine 27 on histone H3 depend on their proximity to chromosome ends and can be induced ectopically by insertion of telomere repeats.
    1. Microbiology and Infectious Disease

    The kinetoplastid-infecting Bodo saltans virus (BsV), a window into the most abundant giant viruses in the sea

    Christoph M Deeg et al.
    Bodo saltans virus defines the most abundant giant viruses in the ocean and highlights the genomic plasticity, rooted in evolutionary arms races, that gave rise to giant viruses.