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Novel insights into LIS1-dependent regulation of cell membrane contractility and cleavage axis specification identify a key molecular network regulating mitoses of neural progenitors and somatic cells during development.

Combining experimental and theoretical approaches reveals the interplay between optogenetic manipulation and recurrent interactions in mouse cortex.

Afferent-derived factors control the elaboration of appropriate and robust sizes of dendritic arbors by dynamically modulating dendritic growth parameters.

Downregulation of mitochondrial activity by immunosuppressive tumor-derived soluble factors leads to systemic unresponsiveness to the PD-1 blockade therapy.

Unique biosensor design and protein-engineering enables direct visualization of the active form of Fyn kinase with high specificity, minimal perturbation and shows cellular signaling to be compartmentalized and pulsatile.

Usage-dependent inhibition breakdown and neural adaptation underpins the key spatiotemporal dynamics of human focal seizures.

A membrane-associated, supramolecular protein complex with dynamically changing components, the central supramolecular activation cluster, regulates the generation of the T cell effector cytokine IL-2 depending on its composition.

The effects of chloride homeostasis can explain diverse responses of basal ganglia output neurons to putatively inhibitory inputs and may tune these neurons' synchrony, oscillations and behavior in decision-making scenarios.

A binary cell fate decision to be or not to be stomata is regulated by multiple peptide ligands, each triggering a unique subcellular dynamics of their shared receptor.

Integration and segregation of information of memory and sensory in the hippocampus could be achieved by the coordination of distinct theta-gamma coding frameworks.