5,792 results found
    1. Neuroscience

    Tactile sensory channels over-ruled by frequency decoding system that utilizes spike pattern regardless of receptor type

    Ingvars Birznieks et al.
    Perception of vibrotactile frequency depends on the neural discharge pattern rather than the afferent type, thus requiring a reevaluation of the notion of Pacinian/non-Pacinian channels in tactile sensory system.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence

    Pavan Vedula et al.
    CRISPR/Cas9 gene editing in mice reveals that diverse functions of actin isoforms are defined by their nucleotide, rather than their amino acid sequence, suggesting a novel mechanism of nucleotide-dependent protein regulation in eukaryotic genomes.
    1. Computational and Systems Biology

    Active contraction of microtubule networks

    Peter J Foster et al.
    Microtubule networks in frog egg extracts can spontaneously contract in a manner that can be quantitatively described by an active fluid model.
    1. Cell Biology
    2. Neuroscience

    Active presynaptic ribosomes in the mammalian brain, and altered transmitter release after protein synthesis inhibition

    Matthew S Scarnati et al.
    Local presynaptic protein synthesis occurring at established nerve terminals in the mammalian brain provides a mechanism for rapidly controlling or restoring presynaptic proteins that affect neurotransmitter release and presynaptic efficiency.
    1. Neuroscience

    Neuropeptide B mediates female sexual receptivity in medaka fish, acting in a female-specific but reversible manner

    Towako Hiraki-Kajiyama et al.
    In the brain of medaka fish, neuropeptide B acts directly downstream of estrogen in a female-specific but reversible manner to mediate female receptivity to male courtship.
    1. Immunology and Inflammation

    Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster

    Naren Srinivasan et al.
    Extracellular actin is an evolutionarily-conserved signal of tissue injury that is recognised in the fruit fly via similar machinery as reported in vertebrates.
    1. Neuroscience

    Monitoring ATP dynamics in electrically active white matter tracts

    Andrea Trevisiol et al.
    ATP imaging of spiking optic nerve axons in real time reveals correlation between ATP levels and electrical activity as well as contribution of lactate metabolism to axonal ATP homeostasis.
    1. Neuroscience

    Adult-born granule cells mature through two functionally distinct states

    János Brunner et al.
    3-10 weeks old adult-born granule cells provide two temporally overlapping but functionally distinct neuronal cell populations by being sensitive to distinct aspects of their inputs.
    1. Physics of Living Systems

    Dynamic density shaping of photokinetic E. coli

    Giacomo Frangipane et al.
    The concentration of motile bacteria, expressing a light-driven proton pump, can be precisely controlled in space and time by spatially modulating their swimming speeds with a structured light pattern.

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