449 results found
    1. Ecology

    Rapid spread of a densovirus in a major crop pest following wide-scale adoption of Bt-cotton in China

    Yutao Xiao, Wenjing Li ... Kongming Wu
    Exposure to Bacillus thuringiensis (Bt) selects for beneficial interactions between the target insect pest (Helicoverpa armigera) and its symbiotic densovirus that enhances its performance on Bt-crops under field conditions.
    1. Genetics and Genomics

    Using adopted individuals to partition indirect maternal genetic effects into prenatal and postnatal effects on offspring phenotypes

    Liang-Dar Hwang, Gunn-Helen Moen, David M Evans
    Adopted individuals in large-scale population based cohorts can be leveraged to partition maternal genetic effects into prenatal and postnatal components, helping elucidate the underlying mechanisms behind these associations, and for diseases, yielding important information regarding the optimal timing of interventions.
    1. Neuroscience

    Common cell type nomenclature for the mammalian brain

    Jeremy A Miller, Nathan W Gouwens ... Amy Bernard
    A new nomenclature convention for mammalian cell types utilizing shared taxonomies and quantitative cell features is applied to high-quality, open data from the mouse and human brain.
    1. Epidemiology and Global Health

    Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up

    Xia Li, Alexander Ploner ... Sara Hägg
    Biological ages have the potential to provide aging-related information beyond chronological age and can be predictive of mortality independently of both chronological age and different types of biological ages.
  1. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan, Liam W Harris, E Richard Gold
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
    1. Ecology

    Social learning mechanisms shape transmission pathways through replicate local social networks of wild birds

    Kristina B Beck, Ben C Sheldon, Josh A Firth
    Social connectivity increases an individual’s likelihood of behavioural adoption if the learning rule depends on the extent of social connections to informed others, but is unrelated when learning depends on the ratio of connections to informed versus uninformed others.
    1. Medicine

    Meta-Research: A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals

    Diana Herrera-Perez, Alyson Haslam ... Vinay Prasad
    An analysis of more than 3000 randomized controlled trials published in JAMA, the Lancet and NEJM has identified 396 medical reversals.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Host-associated microbe PCR (hamPCR) enables convenient measurement of both microbial load and community composition

    Derek S Lundberg, Pratchaya Pramoj Na Ayutthaya ... Detlef Weigel
    hamPCR is a cost-effective and transformative amplicon sequencing strategy to describe microbiota composition and measure its overall abundance, applicable to all samples in which host and microbial DNA are co-extracted.
    1. Epidemiology and Global Health

    Examining the association of clinician characteristics with perceived changes in cervical cancer screening and colposcopy practice during the COVID-19 pandemic: a mixed methods assessment

    Lindsay Fuzzell, Naomi C Brownstein ... Rebecca B Perkins
    Reductions in cervical cancer screening and colposcopy among nearly half of surveyed clinicians more than a year into the COVID-19 pandemic raise concerns that inadequate screening and follow-up will lead to future increases in preventable cancers.
    1. Computational and Systems Biology
    2. Neuroscience

    A reductionist paradigm for high-throughput behavioural fingerprinting in Drosophila melanogaster

    Hannah Jones, Jenny A Willis ... Giorgio F Gilestro
    Coccinella, an open-source framework, combines real-time tracking on microcomputers with statistical learning, optimising behaviour analysis in Drosophila melanogaster while surpassing other advanced systems in throughput and performance.

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