A novel molecular mechanism linking a neurotrophin with a Toll-family and kinase-less Trk-like receptors provides a direct link from molecules to structural circuit plasticity and modification of behaviour.
RNA-Seq analysis and molecular biological approaches reveal a novel mechanism and provide a promising preventive and therapeutic molecular target for vulnerability to chronic pain-related memory impairment.
Maryam Rahimi-Balaei, Shayan Amiri ... Hassan Marzban
A distinct subset of cerebellar nuclei neurons originates from a previously unrecognized germinal zone within the cerebellar primordium, independent of Atoh1 influence, highlighting new cellular origins in cerebellar development.
An in vitro chemical screen with single-cell sequencing output leads to the identification of Metformin as an in vivo enhancer of Muller glia to neuron reprogramming in mice.
A transcriptomic atlas of the mouse vomeronasal organ reveals novel receptor co-expression patterns and provides a framework for understanding sensory neuron lineage and receptor specification.