3,954 results found
    1. Neuroscience

    Bacterial diet affects the age-dependent decline of associative learning in Caenorhabditis elegans

    Satoshi Higurashi, Sachio Tsukada ... Kentaro Noma
    A screen of lactic acid bacteria reveals that diet modulates the age-dependent decline of thermotaxis behavior in C. elegans without changing the organismal lifespan.
    1. Neuroscience

    Infants are superior in implicit crossmodal learning and use other learning mechanisms than adults

    Sophie Rohlf, Boukje Habets ... Brigitte Röder
    Electrophysiological activity indicates superior implicit crossmodal learning in infants and a change in learning mode from infancy to adulthood.
    1. Neuroscience

    Age-dependent predictors of effective reinforcement motor learning across childhood

    Nayo M Hill, Haley M Tripp ... Amy J Bastian
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cancer Biology
    2. Computational and Systems Biology

    Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

    Rosalyn W Sayaman, Masaru Miyano ... Mark A LaBarge
    Breast luminal epithelial cells are the hotspots of aging-associated changes, which prime aged epithelia for oncogenic gene activation and may explain individual differences in breast cancer susceptibility due to the aging-associated increase in gene expression variances in luminal epithelia.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in Caenorhabditis elegans

    Haikel Dridi, Frances Forrester ... Andrew Marks
    The Ryanodine receptor type 1 calcium channels play a critical role in age-related muscle function loss.
    1. Neuroscience

    Neuroscience: Unveiling hidden sources of noise

    Morgan Fitzgerald, Eena Kosik, Bradley Voytek
    Changes in neural activity thought to reflect brain aging may be partly influenced by age-dependent signals ‘leaking’ from the heart.
    Version of Record
    Insight
    1. Cell Biology

    Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration

    Robert J Tower, Emily Busse ... Mimi C Sammarco
    Metabolic supplementation attenuates age-dependent declines in regeneration.
    1. Neuroscience

    Valence biases in reinforcement learning shift across adolescence and modulate subsequent memory

    Gail M Rosenbaum, Hannah L Grassie, Catherine A Hartley
    Relative to children and adults, adolescents placed greater weight on negative prediction errors during learning and these age-varying learning idiosyncrasies biased subsequent memory for information associated with valenced outcomes.
    1. Computational and Systems Biology
    2. Neuroscience

    The interpretation of computational model parameters depends on the context

    Maria Katharina Eckstein, Sarah L Master ... Anne GE Collins
    Context factors such as experimental task and model parameterization can significantly impact modeling results, such that across tasks, the same participants show different fitted parameter values, and parameters capture different cognitive processes across tasks.
    1. Neuroscience

    Persistent firing in LEC III neurons is differentially modulated by learning and aging

    Carmen Lin, Venus N Sherathiya ... John F Disterhoft
    Temporal associative learning enhances persistent firing in lateral entorhinal cortex (LEC) layer III neurons, while aging decreases persistent firing, leading to cognitive impairments.

Refine your results by:

Type
Research categories