15,577 results found
    1. Developmental Biology

    Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

    Weiyi Tang, Megan L Martik ... Marianne E Bronner
    Lineage analysis reveals that cardiac neural crest contributes to cardiomyocytes across vertebrates and consistent with this, the neural crest gene regulatory program is reactivated upon heart regeneration in zebrafish.
    1. Developmental Biology

    Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration

    Edgar M Pera, Josefine Nilsson-De Moura ... Ivana Milas
    An extracellular proteolytic pathway involving the serine protease HtrA1, its inhibitor SerpinE2, and the transmembrane proteoglycan Syndecan-4 control collective migration of neural crest cells in the developing embryo.
    1. Cancer Biology
    2. Computational and Systems Biology

    Comprehensive characterization of tumor microenvironment in colorectal cancer via molecular analysis

    Xiangkun Wu, Hong Yan ... Li Liang
    Integrated molecular analysis demonstrated that colorectal cancer can be classified into four molecular subtypes (proliferative, immunomodulatory, immunosuppressed, and immune-excluded subtypes), providing valuable insight into the intricate relationship between tumor microenvironment heterogeneity and various clinical phenotypes.
    1. Immunology and Inflammation

    IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis

    Qian Wang, Christin M Lepus ... William H Robinson
    Osteoarthritis pathogenesis is driven by IgE-mediated mast cell activation.
    1. Neuroscience

    Drosulfakinin signaling encodes early-life memory for adaptive social plasticity

    Jiwon Jeong, Kujin Kwon ... Chunghun Lim
    Social clustering behaviors in Drosophila are closely tied to compensatory mechanisms for developmental traits and adaptive behavior plasticity, requiring early-life social experiences and the memory-encoding neuropeptide signaling pathway.
    1. Neuroscience

    Disynaptic cerebrocerebellar pathways originating from multiple functionally distinct cortical areas

    Julia U Henschke, Janelle MP Pakan
    Anatomical projections from sensory, motor, and association cortex to the cerebellum are precisely mapped, including cortical-precerebellar connections and terminal organization, providing insight into how the cerebellum may utilize cortical information.
    1. Medicine

    Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy

    Yohei Nitta, Jiro Osaka ... Atsushi Sugie
    Dominant optic atrophy (DOA) and DOA plus mutations' effects on optic nerve degeneration distinguished in a novel Drosophila model.
    1. Immunology and Inflammation

    Amphibian mast cells serve as barriers to chytrid fungus infections

    Kelsey A Hauser, Christina N Garvey ... Leon Grayfer
    Enriching amphibian, Xenopus laevis, cutaneous mast cells confers protection against Batrachochytrium dendrobatidis chytrid fungus infections.
    1. Microbiology and Infectious Disease

    Total parasite biomass but not peripheral parasitaemia is associated with endothelial and haematological perturbations in Plasmodium vivax patients

    João L Silva-Filho, João CK Dos-Santos ... Fabio TM Costa
    Data exploring host and parasite signatures in the peripheral blood indicate that total parasite biomass is a better predictor of P. vivax-induced host responses and pathogenesis than peripheral parasitemia.

Refine your results by:

Type
Research categories