676 results found
    1. Immunology and Inflammation

    Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry

    Valeria Ramaglia et al.
    Imaging mass cytometry simultaneously lights up distinct immune cells in the brain.
    1. Neuroscience

    Metacontrol of decision-making strategies in human aging

    Florian Bolenz et al.
    Older adults show reduced adaptation of decision-making strategies to dynamically changing situational demands.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Self-sperm induce resistance to the detrimental effects of sexual encounters with males in hermaphroditic nematodes

    Lauren N Booth et al.
    Nematode hermaphroditism has co-evolved with a self-sperm sensing mechanism that protects hermaphrodites from the detrimental effects of mating with males.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Aging: A new defense in the battle of the sexes

    George L Sutphin
    Young Caenorhabditis elegans hermaphrodites use their own sperm to protect against the negative consequences of mating.
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    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration

    Zhihao Jia et al.
    Inhibition of Polo-like kinase that has been shown to exhibit antitumor effect unexpectedly disrupts muscle stem cell function, leading to developmental and regenerative failures.
    1. Cell Biology

    A two-step mechanism for the inactivation of microtubule organizing center function at the centrosome

    Jérémy Magescas et al.
    The microtubule organizing potential of the centrosome is inactivated in a stepwise process through phosphatase activity and mechanical disruption to remove an aging matrix of proteins.

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