469 results found
    1. Cancer Biology
    Reproducibility Project

    Reproducibility Project: Cancer Biology

    Curated by Roger Davis et al.
    Investigating reproducibility in preclinical cancer research.
  1. October 2015

    Episode 24: October 2015

    In this episode we hear about Parkinson's Disease, depression, chickenpox, bats, beetles, and how small prey can escape larger predators.
  2. The Author's Story

    The Author's Story: A Series of Interviews

    Curated by Emma Pewsey
    eLife authors answer questions about their life and work.
  3. December 2015

    Episode 26: December 2015

    In this episode we hear about heat-seeking behaviour in mosquitos, mass spawning in coral reefs, social organization in ants, fear in rats and tissue regeneration in newts.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease
    Tropical disease

    Tropical Disease: A Collection of Articles

    Curated by Prabhat Jha et al.
    eLife has published papers on many tropical diseases, including malaria, Ebola, leishmaniases, Dengue and African sleeping sickness.
  4. June 2015

    Episode 21: June 2015

    In this episode we hear about tinnitus and hyperacusis, salamanders, chemical harpoons, and the role of ultrasound and song in the mating rituals of mice and flies.
  5. Episode 38: May 2017

    In this episode we hear about biofilms in bacteria, drug production, gender bias in peer review, nematode worms and how synchronising brain waves can boost memory.
    1. Neuroscience

    Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1

    Jamie McQueen et al.
    Excitotoxicity driven by NMDA receptor hyper-activation does not involve DAPK1-dependent events in vitro or in vivo, and previously described DAPK1-NMDAR disrupting peptides act by blocking the NMDA receptor.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    A novel region in the CaV2.1 α1 subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone

    Matthias Lübbert et al.
    A novel region in the CaV2.1 α1 subunit regulates coupling of synaptic vesicles to CaV2.1 calcium channels, synaptic vesicle release and docking, and the size of the fast and total releasable pools of synaptic vesicles.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status

    Dongming Li et al.
    The METHYL-CpG-BINDING DOMAIN 7 (MBD7) complex promotes the activation (rather than repression) of transgenes that undergo DNA methylation and it does so without significantly altering their methylation status, placing this complex downstream of DNA methylation.

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