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    1. Ecology

    Ocean acidification increases susceptibility to sub-zero air temperatures in ecosystem engineers and limits poleward range shifts

    Jakob Thyrring, Colin D Macleod ... Christopher DG Harley
    A novel experiment shows that ocean acidification decreases freeze tolerance in blue mussels, which may limit their ability to redistribute poleward in response to climate warming.
    1. Cell Biology

    Aurora A depletion reveals centrosome-independent polarization mechanism in Caenorhabditis elegans

    Kerstin Klinkert, Nicolas Levernier ... Pierre Gönczy
    Experiments reveal mechanisms through which Caenorhabditis elegans zygotes depleted of Aurora A or lacking centrosomes spontaneously establish two posterior PAR-2 domains, one at each pole, in a curvature-dependent manner.
    1. Cell Biology

    Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts

    Charlotte Guyomar, Clément Bousquet ... Denis Chrétien
    Tubulin engages unique lateral interactions without longitudinal ones during microtubule polymerization, leaving holes of a few subunits size potentially at the origin of tubulin exchange within their shaft.
    1. Neuroscience

    Distinct combinations of variant ionotropic glutamate receptors mediate thermosensation and hygrosensation in Drosophila

    Zachary A Knecht, Ana F Silbering ... Paul A Garrity
    A combination of genetics, behavior and physiology demonstrate that cool and moisture sensing rely on overlapping combinations of sensory receptors in Drosophila.
    1. Neuroscience

    In vivo imaging with a water immersion objective affects brain temperature, blood flow and oxygenation

    Morgane Roche, Emmanuelle Chaigneau ... Serge Charpak
    Brain temperature and oxygenation vary according to the imaging conditions during two-photon microscopy.
    1. Developmental Biology
    2. Evolutionary Biology

    Bichir external gills arise via heterochronic shift that accelerates hyoid arch development

    Jan Stundl, Anna Pospisilova ... Robert Cerny
    Unique heterochrony in the cranial segments in bichirs triggers the early formation of their external gills, and might be informative about developmental mechanisms facilitating increased breathing capacity.
    1. Neuroscience

    Activity patterns of serotonin neurons underlying cognitive flexibility

    Sara Matias, Eran Lottem ... Zachary F Mainen
    Recordings from serotonin-producing neurons in the brain reveal that these neurons are highly activated by sudden changes in previously familiar environments, potentially explaining why serotonin is important for learning to adapt to such changes.
    1. Cell Biology

    Reconstitution of self-organizing protein gradients as spatial cues in cell-free systems

    Katja Zieske, Petra Schwille
    A minimal cell-like system with defined geometry has been used to investigate the establishment and spatial control of a protein gradient that positions the bacterial cell division machinery.
    1. Evolutionary Biology

    Spinosaurus is not an aquatic dinosaur

    Paul C Sereno, Nathan Myhrvold ... Lauren L Conroy
    A digital flesh model of the sail-backed dinosaur Spinosaurus was tested and performed very poorly in water, favoring the view of this dinosaur as a two-legged, wading ambush predator of large fish in shallow waterways and not an aquatic dinosaur.
    1. Cell Biology
    2. Developmental Biology

    Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium

    Hai Huang, Thomas B Kornberg
    Cytonemes mediate, and are essential for, Wingless signaling from the Drosophila wing disc to disc-associated myoblasts and for Delta-Notch signaling from these myoblasts to the dorsal air sac primordium.