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    1. Genetics and Genomics
    2. Plant Biology

    The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana

    Erik Wijnker, Geo Velikkakam James ... Korbinian Schneeberger
    A comprehensive and genome-wide description of the genomic make-up and frequency of meiotic recombination in Arabidopsis thaliana reveals regional preferences, including nucleosome-free regions, and two associated recombination motifs.
    1. Neuroscience

    Auditory mismatch responses are differentially sensitive to changes in muscarinic acetylcholine versus dopamine receptor function

    Lilian Aline Weber, Sara Tomiello ... Klaas Enno Stephan
    Biperiden, but not amisulpride, delays auditory mismatch responses during environmental stability, suggesting a differential sensitivity of auditory statistical learning to muscarinic versus dopaminergic receptor status which could prove useful for developing tests that predict an individual's response to antipsychotic treatment.
    1. Epidemiology and Global Health

    The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa

    Michelle M Riehle, Tullu Bukhari ... Kenneth D Vernick
    A common chromosome inversion in African malaria mosquito (Anopheles gambiae) is associated with differences in malaria infection, adult resting behavior and ecology, and may aid the most efficient vectors to evade malaria control.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A population-level invasion by transposable elements triggers genome expansion in a fungal pathogen

    Ursula Oggenfuss, Thomas Badet ... Daniel Croll
    The activation of transposable elements and relaxed purifying selection underpin an incipient expansion of the genome in populations of a major wheat pathogen.
    1. Genetics and Genomics
    2. Evolutionary Biology

    Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments

    Christopher S McAllester, John E Pool
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Evolutionary Biology

    Environmental response in gene expression and DNA methylation reveals factors influencing the adaptive potential of Arabidopsis lyrata

    Tuomas Hämälä, Weixuan Ning ... Outi Savolainen
    Environmentally responsive genes evolve under strong selective constraint in Arabidopsis lyrata.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Epistatic selection on a selfish Segregation Distorter supergene – drive, recombination, and genetic load

    Beatriz Navarro-Dominguez, Ching-Ho Chang ... Amanda M Larracuente
    African haplotypes of a meiotic drive supergene in Drosophila melanogaster called Segregation Distorter show signs of a recent selective sweep, reduced recombination, and increased genetic load.
    1. Developmental Biology
    2. Genetics and Genomics

    Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression

    Daniel Andergassen, Christoph P Dotter ... Quanah J Hudson
    Allele-specific expression due to genetic differences, X-chromosome inactivation or genomic imprinting, varies dynamically throughout development, and may be explained by allele-specific differences in stability or the actions of tissue-specific enhancers.
    1. Developmental Biology
    2. Genetics and Genomics

    Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network

    Yamila N Torres Cleuren, Chee Kiang Ewe ... Joel H Rothman
    Quantitative genetic analyses reveal remarkably broad genetic variation underlies the requirement for two critical regulatory inputs into a core embryonic gene regulatory network within one animal species.
    1. Evolutionary Biology

    The genetic architecture of the load linked to dominant and recessive self-incompatibility alleles in Arabidopsis halleri and Arabidopsis lyrata

    Audrey Le Veve, Mathieu Genete ... Vincent Castric
    By modulating the intensity of balancing selection at the S-locus, dominance between self-incompatibility alleles shapes the genetic load linked to each allele, creating inbreeding depression in some S-locus homozygotes.