21 results found
    1. Developmental Biology

    Specialized impulse conduction pathway in the alligator heart

    Bjarke Jensen et al.
    A specialized conduction pathway for the electrical impulse in the heart, previously thought to be associated with the endothermic mammals and birds only, is also present in the ectothermic crocodiles.
    1. Developmental Biology

    Evolution: The beat goes on

    Tobias Wang
    Why is the alligator heart so similar to the hearts of birds and mammals?
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    1. Evolutionary Biology

    Giant extinct caiman breaks constraint on the axial skeleton of extant crocodylians

    Torsten M Scheyer et al.
    The giant caiman Purussaurus from the Miocene of Venezuela is the first recorded member of crown Crocodylia having three sacrals, thus breaking the otherwise strict vertebral constraint of the group.
    1. Evolutionary Biology

    Novel neuroanatomical integration and scaling define avian brain shape evolution and development

    Akinobu Watanabe et al.
    More integrated brains in crown birds evolved through a mosaic assembly of new evolutionary and developmental dynamics across neuroanatomical regions that occurred along the dinosaur-bird transition.
    1. Developmental Biology
    2. Evolutionary Biology

    The alternative regenerative strategy of bearded dragon unveils the key processes underlying vertebrate tooth renewal

    Lotta Salomies et al.
    Analysis of bearded dragon model reveals a novel tooth replacement strategy that demonstrates the critical importance of epithelial patterning, cell migration, and putative stem cell functional specialization in tissue regeneration.
    1. Neuroscience

    ‘Fearful-place’ coding in the amygdala-hippocampal network

    Mi-Seon Kong et al.
    By recording simultaneous spike trains from fear-responsive basal amygdala (BA) and place-responsive dorsal hippocampus (dHPC) neurons in rats foraging for food in a risky predatory situation, a novel BA-dHPC circuit coding mechanism for interfacing danger and place information was revealed.
    1. Developmental Biology
    2. Evolutionary Biology

    Patterning: Fishing for ancestry

    Hannah Brunsdon, E Elizabeth Patton
    The same genes and signalling pathways control the formation of skin appendages in both fish and land animals.
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    1. Neuroscience

    Population rate-coding predicts correctly that human sound localization depends on sound intensity

    Antje Ihlefeld et al.
    Softer sound appears closer to midline than louder sound, conflicting with a labelled-line representation of auditory space and supporting the idea that humans use rate coding when calculating sound directionality.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Immune genes are hotspots of shared positive selection across birds and mammals

    Allison J Shultz, Timothy B Sackton
    Pathogens, particularly viruses, target the same genes over deep evolutionary time, resulting in shared signatures of positive selection and transcriptional responses at the same genes.
    1. Immunology and Inflammation

    Endomembrane targeting of human OAS1 p46 augments antiviral activity

    Frank W Soveg et al.
    Prenylation of human oligoadenylate synthetase 1 isoform p46 mediates endomembrane targeting and increases its antiviral activity against positive-strand RNA viruses that utilize the host endomembrane system for replication.

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