IL-27 exerts differential activation of STAT1 and STAT3 via IL-27Ra and GP130, respectively, leading to a kinetic decoupling of its gene expression program, which contributes to tune its immuno-modulatory activities.

Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.

The genome of a tiny tomato pest reveals mechanisms that underlie metazoan genome reduction.

The proposed method deciphers which low-level patterns (such as spikes) control high-level features (behavior) in relative small biological datasets, taking into account the statistical dependencies between such patterns.

Enantiornithine birds reached similar dietary diversity to modern birds in a similar amount of time many millions of years earlier, but how exactly they did that requires further research.

Individuals with a history of adverse childhood experiences show blunted response to threat and reward irrespective of sample and paradigm characteristics and despite heterogeneity in adversity operationalization and assessment.

A new taxon from the Late Jurassic of southern Germany represents the second volant bird known from that time period and documents the improvement of flapping flight in bird evolution.

Switches in cell state downstream of pathogen exposure are driven by a deeply conserved disorder-to-order phase transition in an immunity signaling network.