Perturbations in the extracellular environment drive transitions from a highly stable memory state to an alternative phenotype in microorganisms.

Analysis of microbial communities in floral nectar shows that it is possible to identify an overarching factor that governs the eco-evolutionary dynamics of priority effects across multiple levels of biological organization.

Multistability and regime shifts are common and species diversity is high in microbial communities when nutrient supplies are balanced and competing species have different stoichiometries of essential nutrients.

Circuit-wide calcium imaging during C. elegans foraging elucidates the functional architecture of a neural circuit controlling the choice between two alternative behavioral states.

Protein conformational heterogeneity changes upon ligand binding are influenced by ligand properties and can modulate the free energy of binding.

Phosphorylation of Aurora A does not trigger a population shift to the active state as previously thought, but instead switches the kinase on by tuning the structure and dynamics of a dynamically sampled subpopulation.

An ancestral helical bundle governs whether the crRNA-processing nuclease of CRISPR-Cas12a is exploited by a phage-encoded allosteric anti-CRISPR.

Single unit recordings in monkeys and biophysical modelling demonstrate that local inhibitory-controlled metastable neural states specify the temporal organization of cognitive functions in frontal areas.

Evidence for a largely unexplored radiation of squamates (lizards, snakes, and amphisbaenians) in the Middle to Late Jurassic is revealed by analyses of morphospace expansion, disparity, and evolutionary rates.