612 results found
    1. Neuroscience

    Strikingly different neurotransmitter release strategies in dopaminergic subclasses

    Ana Dorrego-Rivas, Darren J Byrne ... Matthew S Grubb
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Neuroscience

    Combined transcriptomic, connectivity, and activity profiling of the medial amygdala using highly amplified multiplexed in situ hybridization (hamFISH)

    Mathew D Edwards, Ziwei Yin ... Yoh Isogai
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Medicine

    Sperm fertility in mice with oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA

    Charline Vilpreux, Guillaume Martinez ... Jessica Escoffier
    Revised
    Reviewed Preprint v2
    Updated
    • Inadequate
    1. Immunology and Inflammation

    Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

    Ziyu Wen, Pingchao Li ... Caijun Sun
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Developmental Biology

    Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition

    Anastasiia Lozovska, Ana Casaca ... Moises Mallo
    Tgfbr1 signaling governs all processes associated with the trunk to tail transition, including the repositioning of neuro-mesodermal progenitors, as well as the remodeling of the lateral plate mesoderm and embryonic endoderm.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Risk factors affecting polygenic score performance across diverse cohorts

    Daniel Hui, Scott Dudek ... Marylyn D Ritchie
    Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.
    1. Neuroscience

    Discriminating neural ensemble patterns through dendritic computations in randomly connected feedforward networks

    Bhanu Priya Somashekar, Upinder Singh Bhalla
    In feedforward networks with random connectivity, connection motifs underlying the detection of short clusters and activity sequences are likely to converge on a subset of postsynaptic neurons purely by chance.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective

    Joseph Ackermann, Chiara Bernard ... Martine Ben Amar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex

    Claire Meissner-Bernard, Friedemann Zenke, Rainer W Friedrich
    Computational modeling revealed that balanced assemblies of excitatory and inhibitory neurons shape representational manifolds in olfactory cortex-like recurrent networks, resulting in joint maps of sensory and semantic information.

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