Two different classes of taste receptor neurons in the Drosophila melanogaster proboscis play distinct roles in yeast feeding and are both modulated by the fly's internal amino acid state in order to promote protein-specific appetite.

During perceptual decision-making, some errors on easy decisions (lapses) are not simply mistakes, but instead reflect strategic decisions to explore actions associated with uncertain rewards.

A cell-free biochemical assay for protein lipidation identifies the ER–Golgi intermediate compartment as a key early station in the formation of an autophagosome.

The BRAIN Initiative data-sharing ecosystem, consisting of seven data archives, faces interoperability and data stewardship challenges but nevertheless offers adaptability to the needs of particular research communities and raw material for network evolution.

KASH5 uses an EF-hand domain to directly interact with the light intermediate chain of dynein, promotes processive dynein motility, and facilitates dynein recruitment to the nuclear envelope during prophase I of meiosis.

Transcriptional activation domains achieve rapid, dynamic, specific interaction with Mediator through binding of an unstructured peptide to multiple hydrophobic surfaces without particular amino acid side chain interactions.