The generation and systematic characterisation of driver lines labelling a large number of neurons in the Drosophila innate olfactory processing centre bridges electron microscopy neuronal reconstructions, circuits and behaviour.
A quantitative analysis of glucose-dependent transport regulation indicates that mitochondrial accumulation in regions of high nutrient availability can enhance metabolism in neuronal axons under physiologically relevant conditions.
Motivation for flight and feeding behaviour requires dopamine release which depends on cholinergic stimulation and intracellular Ca2+ release from ER stores in one or two pairs of central dopaminergic neurons.
Brain imaging and behavioral analysis reveal two opposing states of hunger, represented by anti-correlated lateral and caudal hypothalamic dynamics that are important for the homeostatic control of feeding in zebrafish.
Lattice light-sheet single-molecule imaging shows 3D Sox2 enhancer clusters in live embryonic stem cells and reveals a model linking 3D spatial distribution of cis-elements, differential target search features and localized gene regulation.