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    1. Cancer Biology

    STAMBPL1 activates the GRHL3/HIF1A/VEGFA axis through interaction with FOXO1 to promote angiogenesis in triple-negative breast cancer

    Huan Fang, Huichun Liang ... Ceshi Chen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Developmental Biology

    Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

    Madeline M Keenen, Liheng Yang ... Carolyn B Coyne
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    An atypical basement membrane forms a midline barrier during left-right asymmetric gut development in the chicken embryo

    Cora Demler, John Coates Lawlor ... Natasza A Kurpios
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    • Convincing
    1. Microbiology and Infectious Disease

    Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced aberrant calcium transient

    Yuki Tatekoshi, Chunlei Chen ... Hossein Ardehali
    A calcium transient measurement system utilizing human induced pluripotent stem cell-derived cardiomyocytes reveals the detrimental impact of inflammatory cytokines on cardiomyocyte relaxation and displays the potential of drugs to reverse these defects.
    1. Genetics and Genomics

    Dysfunction of Calcyphosine-Like gene impairs retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy

    Wenjing Liu, Shujin Li ... Xianjun Zhu
    Genetic analysis and knockout mouse model study identified calcyphosine-like (CAPSL) as a candidate disease gene in familial exudative vitreoretinopathy (FEVR), offering valuable insights into disease mechanisms.
    1. Cancer Biology

    Single-cell dissection of prognostic architecture and immunotherapy response in Helicobacter pylori infection associated gastric cancer

    Xin Zhang, Guangyu Zhang ... Chunjie Liu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cancer Biology

    Exploring the role of the immune microenvironment in hepatocellular carcinoma: Implications for immunotherapy and drug resistance

    Yumin Fu, Xinyu Guo ... Lianxin Liu
    The immune microenvironment has a pivotal role in hepatocellular carcinoma (HCC) progression and immune therapy resistance, and targeting this complex milieu holds great promise for improving therapeutic outcomes and patient prognoses in HCC management.
    1. Immunology and Inflammation

    Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune response

    Harshavardhan Lingegowda, Katherine B Zutautas ... Chandrakant Tayade
    Cannabinoid receptors CNR1 and CNR2 play distinct roles in endometriosis pathogenesis, potentially contributing to disease initiation and progression through differential modulation of T cell function and the lesion microenvironment.