5,695 results found
    1. Evolutionary Biology

    Evolution: Oxygen and early animals

    Kalle T Rytkönen
    The biology of sponges provides clues about how early animals may have dealt with low levels of oxygen.
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    1. Computational and Systems Biology

    Synthetic Biology: Minimal cells, maximal knowledge

    Jean-Christophe Lachance et al.
    Modeling all the chemical reactions that take place in a minimal cell will help us to understand the fundamental interactions that power life.
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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Distinct RanBP1 nuclear export and cargo dissociation mechanisms between fungi and animals

    Yuling Li et al.
    Animal RanBP1 nuclear export and cargo dissociation mechanisms are surprisingly different from yeast, due to mutations of critical residues, leading to greater nuclear transport efficiency and higher energy cost.
    1. Cell Biology
    2. Developmental Biology

    Apical targeting of the formin Diaphanous in Drosophila tubular epithelia

    Tal Rousso et al.
    Synergistic interactions with PI(4,5)P2 and activated Rho1, which are enriched at the apical membrane of tubular organs, facilitate tight apical targeting of the formin Diaphanous.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Dynamics of genomic innovation in the unicellular ancestry of animals

    Xavier Grau-Bové et al.
    The foundations of genomic complexity in multicellular animals have deep roots in their unicellular prehistory, both in terms of innovations in gene content, as well as the evolutionary dynamics of genome architecture.
    1. Cell Biology
    2. Developmental Biology

    Uncoupling apical constriction from tissue invagination

    SeYeon Chung et al.
    Spatially coordinated apical constriction occurs during Drosophila salivary gland invagination, but the salivary gland can form fully internalized and elongated tubes even when this process is completely blocked.
    1. Developmental Biology

    Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

    Jennifer J Banerjee et al.
    Meru is a factor that provides tissue-specific information to the core polarity machinery by linking planar to apical-basal polarity in asymmetrically dividing sensory organ precursors.
    1. Developmental Biology

    Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination

    Ioannis Kasioulis et al.
    Microtubules are nucleated by the centrosome of the primary cilium in the apical end-foot of neuroepithelial cells and inter-dependent microtubule and actin dynamics are required here to orchestrate delamination of newborn neurons.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Human axial progenitors generate trunk neural crest cells in vitro

    Thomas JR Frith et al.
    Pluripotent stem cell differentiation provides insight into how neural crest subtypes of distinct axial identity are patterned in human embryos.
    1. Ecology
    2. Evolutionary Biology

    Signal categorization by foraging animals depends on ecological diversity

    David William Kikuchi et al.
    In richer, more even communities, foragers form broad categories among their food resources that can select for convergence among signals, including mimetic resemblances.

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