Derepression of transcripts from hypomethylated pericentromeric repeats triggers an innate immune response in an animal model of Immunodeficency, Centromere and Facial anomalies (ICF) syndrome.

Animal studies of fatty liver disease over-estimate the benefit of drugs due to publication bias and are confounded by off-target weight loss, illustrating the challenge of successful translational across species.

Brain lactate and pH changes, identified as common features in diverse neuropsychiatric animal models, may represent transdiagnostic endophenotypes associated with cognitive impairment.

A new deep-learning software toolkit with general-purpose methods for quickly and reliably measuring the full body posture of animals directly from images or videos without physical markers.

The introduction of infectious pathogens to a simulated animal population leads to rapid evolutionary transitions in how individuals move in a social context, with distinct movement morphs evolved that make trade-offs between sociality and infection risk.

A novel animal model of economic decision-making captures complex patterns of choice behavior similar to those of humans, opening the way for mechanistic studies to probe the neural basis for this important form of executive function.

The first malacostracan genome sequence will establish the genetically tractable Parhyale hawaiensis as a model organism in this key animal group.

Correlative imaging of the heart at multiple spatial scales has the potential to revolutionize the way we understand deficiencies in congenital heart disease.

Administration of cryopreserved as compared freshly cultured MSCs do not appear to negatively impact measures of in vivo efficacy or in vitro potency in animal models of inflammation.

Crosses of loaches with various genetic and karyptype divergence cause different reproductive outcomes in hybrids, ranging from sexual reproduction to sterility, inviability, and clonality among females.