9,151 results found
    1. Cell Biology
    2. Immunology and Inflammation

    Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures

    Shannon Rausser, Caroline Trumpff ... Martin Picard
    A high-throughput mitochondrial phenotyping approach quantifies mitochondrial features among purified human immune cell subtypes and provides foundational knowledge to map inter- and intra-individual variation in mitochondrial energetics with high biological specificity.
    1. Neuroscience

    An extended retinotopic map of mouse cortex

    Jun Zhuang, Lydia Ng ... Jack Waters
    An expanded map of mouse cortex reveals the expansion of retinotopic organization into barrel and retrosplenial cortices.
    1. Microbiology and Infectious Disease

    Typhoid toxin sorting and exocytic transport from Salmonella Typhi-infected cells

    Shu-Jung Chang, Yu-Ting Hsu ... Jorge E Galan
    A multidisciplinary approach provides a description of the exocytic pathway that exports Salmonella Typhi's typhoid toxin from infected cells.
    1. Developmental Biology

    Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification

    Heejin Nam, Shin Jeon ... Seunghee Lee
    Shh, produced by postmitotic spinal neurons, plays crucial roles in the specification of the lateral motor column of the spinal cord through ARHGAP36.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Single-cell analysis of the aged ovarian immune system reveals a shift towards adaptive immunity and attenuated cell function

    Tal Ben Yaakov, Tanya Wasserman ... Yonatan Savir
    The ovarian immune system ages while coping with the two main challenges of the aging ovary before menopause, the inflammatory stimulations due to repeated cycles and the increasing need for clearance of accumulating atretic follicles.
    1. Neuroscience

    Range, routing and kinetics of rod signaling in primate retina

    William N Grimes, Jacob Baudin ... Fred Rieke
    Signals from primate rod photoreceptors do not exhibit the light-level-dependent routing through parallel retinal circuits observed in rodents and often invoked in interpreting psychophysical experiments.
    1. Neuroscience

    The causal role of auditory cortex in auditory working memory

    Liping Yu, Jiawei Hu ... Jinghong Xu
    Auditory cortex is essential for information encoding and maintenance in auditory working memory, especially during the early delay period.
    1. Neuroscience

    LRRTM1 underlies synaptic convergence in visual thalamus

    Aboozar Monavarfeshani, Gail Stanton ... Michael A Fox
    The synaptic cell adhesion molecule, leucine-rich repeat transmembrane neuronal 1 (LRRTM1), plays an important role in the establishment of retinal convergence onto relay cells in mouse visual thalamus.
    1. Neuroscience

    Analyzing the brainstem circuits for respiratory chemosensitivity in freely moving mice

    Amol Bhandare, Joseph van de Wiel ... Nicholas Dale
    Recordings from brainstem nuclei involved in chemosensory regulation of breathing in awake freely behaving mice show different complementary types of neuronal responses to hypercapnia in the retrotrapezoid nucleus and the rostral medullary raphe.
    1. Developmental Biology
    2. Genetics and Genomics

    Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm

    Elizabeth M Sefton, Mirialys Gallardo ... Gabrielle Kardon
    HGF derived from fibroblasts is critical for complete muscularization of the mammalian diaphragm, and loss-of-function experiments reveal that partial muscularization of the diaphragm is not sufficient to cause congenital diaphragmatic hernias.

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