A hub in the rostral anterior cingulate cortex receives unusually high and functionally diverse inputs, providing a biological interface between motivation, incentive based learning, and decision making.
A fast spiking interneuron sub-type in medial and lateral prefrontal cortex fires and gamma-synchronizes prominently during adaptive learning of reward values when outcomes are uncertain and choice options have similar values.
Amphetamine reduces reward signaling by neurons in rat prefrontal cortex, but increases the stability of population dynamics, which account for animals’ increased task engagement, despite reduced reward motivation.
The anterior cingulate cortex intermixes a precise spatial map with a cognitive map of the task, and spontaneously recalls multimodal information about unrealized choice outcomes during pauses in behavior after reinforcements.
In vivo quantitative analysis of multi-shell diffusion MRI reveals novel insights into microstructure of human insular cortex and its functional circuits associated with the salience network and cognitive control.
Determining that microbiota-deficient mice have increased visceral pain, which can be reversed by restoring microbiota, may lead to novel microbial-based strategies for disorders associated with visceral pain.