A hub in the rostral anterior cingulate cortex receives unusually high and functionally diverse inputs, providing a biological interface between motivation, incentive based learning, and decision making.
The anterior cingulate cortex intermixes a precise spatial map with a cognitive map of the task, and spontaneously recalls multimodal information about unrealized choice outcomes during pauses in behavior after reinforcements.
Amphetamine reduces reward signaling by neurons in rat prefrontal cortex, but increases the stability of population dynamics, which account for animals’ increased task engagement, despite reduced reward motivation.
Multivariate data decomposition applied to local field potentials recorded from the primate amygdala revealed simultaneously active and functionally distinct networks, defined by anatomical boundaries between the nuclei.
M2 cortex-dorsolateral striatum circuit is functionally altered in Huntington's disease and, by boosting its activity, we reverse symptoms at behavioral, physiological, and morphological level in symptomatic mice.