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In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Phytoplasma effector SAP54 hijacks previously unknown MADS-box protein roles in plant-insect interactions by modulating plant biotic stress responses to male leafhoppers and facilitating female attraction and reproduction on male-exposed leaves.

Chemotherapy remodels lung adenocarcinoma’s tumor microenvironment by driving metabolic reprogramming and shifting immune cell functions to modulate tumor progression and immune responses.

Genetic loss-of-function approaches and functional calcium imaging reveal cholecystokinin as the primary regulator of follicle-stimulating hormone in zebrafish, redefining our understanding of gonadotropin regulation in vertebrates.

Gasdermin D-mediated neutrophil pyroptosis plays an important role in driving inflammation in psoriasis, which unravels new pathogenesis of psoriasis and provides new insights into psoriasis treatment by targeting neutrophil pyroptosis.

Systems analysis of antibody repertoires reveals that strong humoral responses lead to extensive B-cell overlap across multiple lymphoid organs, indicating physiological axes of B-cell migration and a direct correlation with antigen specificity.