Marta Perera, Silas Boye Nissen ... Joshua M Brickman
The simultaneous expansion of G1 and acceleration of the cell cycle, while ensuring synchronous inheritance of these properties, progressively induces cell identity in differentiation.
Artem Mikelov, Evgeniia I Alekseeva ... Ivan V Zvyagin
High degree of clonal persistence and excess of inter-individual convergence are observed in human memory B cell repertoires, along with signatures of both negative and positive selection in most abundant clonal lineages.
Ethan Ozment, Arianna N Tamvacakis ... Nagayasu Nakanishi
Developmental genetics of sea anemone mechanosensory neurons provides insights into the deep evolutionary history of mechanoreceptor development in animals.
A fully synthetic library of humanized single domain antibodies yields in vitro high affinity antibodies usable in cell biology and translational projects.
B-cell integrin co-stimulation promotes the formation of an actomyosin network that drives integrin-dependent immune synapse formation and B-cell activation.
Iga Kucharska, Elaine Thai ... Jean-Philippe Julien
A comprehensive structural analysis of inhibitory murine antibody 3D11 binding to Plasmodium berghei circumsporozoite protein reveals common mechanisms of antibody evolution in mammals against Plasmodium parasites.
ATM plays an important role in maintaining the fidelity of DNA repair through the regulation of ARP8 phosphorylation to prevent the chromosome abnormality.
Kendall J Lough, Kevin M Byrd ... Scott E Williams
Telophase reorientation corrects errors in spindle orientation that persist after imprecise initial spindle positioning during early mitosis, and contributes to balancing self-renewal with differentiation during epidermal development.
