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Neurophysiological signatures of motor preparation reveal countervailing value biasing mechanisms that evolve across consecutive phases of anticipation, detection, and discrimination in sensorimotor decision making.

Two non-overlapping neural circuits that involve the lamina terminalis and arcuate nucleus of hypothalamus independently drive feedforward anticipatory suppression and activation of vasopressin neurons by drinking and feeding, respectively.

Decoding of neural outcome and response representations allows dissecting goal-directed and habitual contributions to behaviour and reveals how acute stress biases the instrumental control of behaviour.

The rodent orbitofrontal cortex makes functionally distinct contributions to flexible behavioural control, even within a single putative orbitofrontal subregion, which has important implications for establishing homology between rodent and primate orbitofrontal cortex.

Building on previous work (Faull et al, 2016), it shown that the different connectivity profiles of the individual columns of the human periaqueductal gray support their proposed roles in human threat behaviours, such as freezing or fight/flight.

Excitatory output neurons in dorsomedial prefrontal cortex display heterogeneously specialized coding properties that evolve during cue-reward learning and predict cue-driven reward seeking.

Pharmacological and genetic studies in the mouse reveal how dopamine D2 receptors on cholinergic interneurons regulate cue-evoked changes in the levels of striatal acetylcholine and dopamine during behavior.

The brain contains a hierarchy of anticipatory signals, with more anterior regions showing anticipation that reaches further into the future.

High-resolution imaging shows that the different columns of the human periaqueductal gray play differential roles in the response to a respiratory threat.

Direct and indirect pathways in the basal ganglia have opposing effects not only on action performance but also on internal timing of expected reward delivery.