There is substantial individual variation in behavioral and neural responses to acute ketamine administration in healthy controls, which emphasises the need for personalized approaches when harnessing ketamine as a treatment for depression.
Vilazodone could bind to the 5-Hydroxtrayptamine receptor 1A receptor and further regulate the SRC/MAPK signaling pathway to facilitate megakaryocyte differentiation and platelet production.
Laure Mignerot, Clotilde Gimond ... Christian Braendle
Caenorhabditis elegans egg-laying behaviour shows pronounced variation in natural populations, making it a promising model to investigate the microevolution of a simple neural circuit.
Participants' subjective beliefs about the treatment received in an intervention study can explain variability in mental health symptoms and cognition.
Brain lactate and pH changes, identified as common features in diverse neuropsychiatric animal models, may represent transdiagnostic endophenotypes associated with cognitive impairment.
Lukas Leopold Lengersdorff, Isabella C Wagner ... Claus Lamm
After playing violent video games for 7 hr over the course of 2 weeks, human male participants show neither signs of decreased empathy for the pain of another person nor of decreased responsivity to violent images.
