371 results found
    1. Neuroscience

    Alterations in the amplitude and burst rate of beta oscillations impair reward-dependent motor learning in anxiety

    Sebastian Sporn et al.
    State anxiety alters the dynamics of beta oscillations during reward-dependent motor learning, thereby impairing proper updating of motor predictions when learning in unstable environments.
    1. Neuroscience

    Altered hippocampal-prefrontal communication during anxiety-related avoidance in mice deficient for the autism-associated gene Pogz

    Margaret M Cunniff et al.
    In POGZ heterozygous mice, reduced anxiety-related avoidance is associated with decreased feedforward inhibition and theta synchrony in the hippocampal-prefrontal pathway.
    1. Neuroscience

    Modulation of anxiety and fear via distinct intrahippocampal circuits

    Elif Engin et al.
    The hippocampus features a double dissociation in its circuits with respect to the regulation of fear and anxiety, with CA3 and the dentate gyrus implicated in anxiety and CA1 in fear.
    1. Neuroscience

    Anxiety dissociates the adaptive functions of sensory and motor response enhancements to social threats

    Marwa El Zein et al.
    Social threats trigger enhanced neural representations within 200 milliseconds in sensory and motor systems of the human brain as a function of anxiety, highlighting its adaptive function in reacting rapidly to dangers in the environment.
    1. Neuroscience

    Threat of shock increases excitability and connectivity of the intraparietal sulcus

    Nicholas L Balderston et al.
    Multimodal neuroimaging was used to study the effect of threat on spontaneous brain activity and functional connectivity, and demonstrated that threat increases both activity and connectivity of the intraparietal sulcus, a key node in the frontoparietal attention network.
    1. Neuroscience

    Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior

    Jordan G McCall et al.
    Selective activation of locus coeruleus noradrenergic terminals drives anxiety-like behaviors through activation of β-adrenergic receptors in the basolateral amygdala.
    1. Neuroscience

    TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala

    Ke-Xin Li et al.
    SOM+ GABAergic neuronal signaling and inhibitory transmission in the central lateral amygdala is regulated by TMEM16B, which is also involved in fear and anxiety-like behaviors.
    1. Neuroscience

    Increased anxiety and decreased sociability induced by paternal deprivation involve the PVN-PrL OTergic pathway

    Zhixiong He et al.
    The PVN-mPFC OT circuit is an important target for the treatment of disorders related to early adverse experiences.
    1. Neuroscience

    A human subcortical network underlying social avoidance revealed by risky economic choices

    Johannes Schultz et al.
    The subjective value of engaging in human social situations, and amygdala and nucleus accumbens activation and their connectivity during social decision-making, vary with social anxiety traits.
    1. Neuroscience

    Impaired adaptation of learning to contingency volatility in internalizing psychopathology

    Christopher Gagne et al.
    Hierarchical modeling of internalizing symptoms and task performance reveals that difficulty adapting probabilistic learning to second-order uncertainty is common to anxiety and depression and holds across rewarding and punishing outcomes.

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