4,976 results found
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function

    Silvia Portugal et al.
    Atypical memory B cells (MBCs) appear to differentiate from classical MBCs during chronic exposure to the malaria parasite Plasmodium falciparum, and may interfere with the acquisition of immunity to the disease.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration

    Aida Rodrigo Albors et al.
    During axolotl spinal cord regeneration adult neural stem cells reactivate an embryonic neuroepithelial cell-like gene program that implements planar cell polarity to orient cell divisions, coupling polarized spinal cord growth with stem cell self-renewal.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Human axial progenitors generate trunk neural crest cells in vitro

    Thomas JR Frith et al.
    Pluripotent stem cell differentiation provides insight into how neural crest subtypes of distinct axial identity are patterned in human embryos.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Plasmodium-specific atypical memory B cells are short-lived activated B cells

    Damián Pérez-Mazliah et al.
    Plasmodium-specific atypical memory B cells generated to naturally (mosquito) transmitted rodent malaria infection are short-lived activated B cells, and do not prevent resolution of infection or generation of long-lived memory.
    1. Plant Biology

    LEAFY maintains apical stem cell activity during shoot development in the fern Ceratopteris richardii 

    Andrew RG Plackett et al.
    Transgenic analysis reveals a role for LEAFY in ferns that supports a trajectory from general to floral meristem-specific function as land plants evolved.
    1. Developmental Biology

    Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division

    Jennifer J Banerjee et al.
    Meru is a factor that provides tissue-specific information to the core polarity machinery by linking planar to apical-basal polarity in asymmetrically dividing sensory organ precursors.
    1. Cell Biology
    2. Neuroscience

    Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells

    Matthew J Sternfeld et al.
    Stem cell derived ventral-spinal cord excitatory neurons self-assemble into a rhythmically bursting neural network whose speed and intercellular coordination are both instructively modulated by cell-type specific interactions with inhibitory neurons.
    1. Developmental Biology

    The invariant cleavage pattern displayed by ascidian embryos depends on spindle positioning along the cell's longest axis in the apical plane and relies on asynchronous cell divisions

    Rémi Dumollard et al.
    Cell cycle asynchrony regulates apical cell shape to drive cell division orientation in the apical plane.
    1. Cell Biology
    2. Developmental Biology

    Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network

    Torey R Arnold et al.
    In epithelial cells, anillin organizes the medial-apical actomyosin cortex into a contractile load-bearing structure and increases tissue-level stiffness.
    1. Cell Biology
    2. Computational and Systems Biology

    Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length

    Shixuan Liu et al.
    The p38 MAPK pathway functions downstream of a cell-size-sensing process to coordinate cell size/growth with G1 progression in animal cells.

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