1,828 results found
    1. Developmental Biology
    2. Evolutionary Biology

    Evolutionary expansion of apical extracellular matrix is required for the elongation of cells in a novel structure

    Sarah Jacquelyn Smith et al.
    A new morphological structure evolved through extreme changes in cell height requires novel connections to an extracellular matrix network, which predates the origin of structure.
    1. Developmental Biology
    2. Evolutionary Biology

    Extracellular Matrix: Sculpting new structures

    Jocelyn A McDonald, Yoshinori Tomoyasu
    The origins of the posterior lobe, a recently evolved structure in some species of Drosophila, have become clearer.
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    1. Neuroscience

    A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin β1 subunit, Lamb1

    Yi Bessie Liu et al.
    A mouse with a defined mutation in an extracellular matrix protein that is expressed in selected neurons sheds light on circuit abnormalities producing transient hyperkinetic movements.
    1. Cell Biology
    2. Physics of Living Systems

    Interplay of cell dynamics and epithelial tension during morphogenesis of the Drosophila pupal wing

    Raphaël Etournay et al.
    Autonomous patterns of cell contraction in the context of localized apical extracellular matrix constraints specify tissue stresses that reshape the wing epithelium.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Nanoscale protein architecture of the kidney glomerular basement membrane

    Hani Suleiman et al.
    High-resolution optical microscopy is used to reveal the organization of extracellular matrix proteins within the basement membrane of the blood filtration barrier in the kidney at the nanometer scale.
    1. Developmental Biology
    2. Evolutionary Biology

    Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues

    Aaron L Fidler et al.
    Collagen IV is a primordial extracellular matrix component associated with the transition to animal multicellularity, and enabled the formation and evolution of epithelial tissues.
    1. Cell Biology
    2. Developmental Biology

    FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis

    Melissa Kelley et al.
    A fibrillin-related protein, FBN-1, is a key component of the apical extracellular matrix and prevents epidermal cell deformation by biomechanical forces during morphogenesis of the C. elegans embryo.
    1. Cell Biology
    2. Developmental Biology

    A feedback mechanism converts individual cell features into a supracellular ECM structure in Drosophila trachea

    Arzu Öztürk-Çolak et al.
    Cell-cell junctions and the actin cytoskeleton are key players in the organisation and patterning of the extracellular matrix (ECM) on the apical side of tracheal cells.
    1. Evolutionary Biology

    Multicellularity: From brief encounters to lifelong unions

    Bradley JSC Olson
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