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    1. Developmental Biology

    Type XVII collagen coordinates proliferation in the interfollicular epidermis

    Mika Watanabe et al.
    Type XVII collagen, a transmembranous protein in basal keratinocytes, suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis.
    1. Neuroscience

    Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function

    Bo Zhao et al.
    Super-resolution microscopy reveals a highly organized compartment in the stereocilia of mechanosensory hair cells of the inner ear, which is critical for hair cell function and affected in disease.
    1. Cell Biology
    2. Developmental Biology

    Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle

    Chet Huan Oon, Kenneth E Prehoda
    Neural stem cells dynamically polarize through the stepwise activity of polarized cortical targeting and cortical flows that coalescence discontinuous cortical patches into an organized cap structure.
    1. Cell Biology
    2. Developmental Biology

    Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure

    Ian A Swinburne et al.
    The pressure of fluid in the inner ear is controlled by opening of cellular valves in the endolymphatic sac to allow for regulated transepithelial fluid flow.
    1. Developmental Biology
    2. Neuroscience

    Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

    Nereo Kalebic et al.
    Expression of human-specific gene ARHGAP11B in the developing ferret neocortex leads to an increase in abundance of neural progenitor cells, which results in neocortex expansion.
    1. Cell Biology
    2. Computational and Systems Biology

    Highly localized intracellular Ca2+ signals promote optimal salivary gland fluid secretion

    Takahiro Takano et al.
    Measurement of physiological intracellular Ca2+ signals following neural stimulation in vivo reveals distinct spatiotemporal characteristics that promote optimal salivary gland fluid secretion.
    1. Developmental Biology

    Signals from the brain and olfactory epithelium control shaping of the mammalian nasal capsule cartilage

    Marketa Kaucka et al.
    The brain and olfactory epithelium play a key role in pattering chondrogenic areas in the developing face, which is partly based on the release of SHH from neurosensory structures into the facial mesenchyme.
    1. Developmental Biology
    2. Neuroscience

    Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia

    Xin Heng et al.
    Genome-wide transcriptional profiling and genetic analyses reveal conserved mechanisms underlying the generation of neocortical basal radial glia and cerebellar Bergmann glia.
    1. Computational and Systems Biology
    2. Neuroscience

    Connectivity map of bipolar cells and photoreceptors in the mouse retina

    Christian Behrens et al.
    A quantitative analysis of the connectivity between photoreceptors and bipolar cells in the mouse retina based on electron microscopy data yields exceptions from established rules of outer retinal connectivity.
    1. Cell Biology
    2. Developmental Biology

    Flattop regulates basal body docking and positioning in mono- and multiciliated cells

    Moritz Gegg et al.
    In cell types that acquire planar cell polarity, the protein Flattop regulates basal body docking and positioning.