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    1. Microbiology and Infectious Disease

    A Novel Rapid Host Cell Entry Pathway Determines Intracellular Fate of Staphylococcus aureus

    Marcel Rühling, Fabio Schmelz ... Martin J Fraunholz
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

    Yingying Chen, Jeong Han Lee ... Ebenezer N Yamoah
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Cancer Biology

    Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies

    Sander Frank, Thomas Persse ... Peter S Nelson
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Developmental Biology

    Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

    Pengzhen Dong, Yue Li ... Hai Huang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Computational and Systems Biology

    Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage

    Zhiwei Huang, Songhao Luo ... Jiajun Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Novel Nuclear Roles for Testis-Specific ACTL7A and ACTL7B Supported by In Vivo Characterizations and AI Facilitated In Silico Mechanistic Modeling with Implications for Epigenetic Regulation in Spermiogenesis

    Pierre Ferrer, Srijana Upadhyay ... Tracy M. Clement
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    EDF1 coordinates cellular responses to ribosome collisions

    Niladri K Sinha, Alban Ordureau ... Rachel Green
    Endothelial Differentiation Factor 1 (EDF1) plays a critical role in driving mRNA-specific quality control and global transcriptional responses in response to ribosome collisions.
    1. Cell Biology
    2. Evolutionary Biology

    The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death

    Nicole L Nuckolls, Anthony C Mok ... Sarah E Zanders
    The Wtf4 antidote protein assembles with the Wtf4 poison protein and promotes the transportation of the assembled proteins to the vacuole for sequestration or destruction.
    1. Cell Biology

    Cell membrane glycan contents are biochemical factors that constitute a kinetic barrier to viral particle uptake in a protein-nonspecific manner

    Yoshihisa Kaizuka, Rika Machida
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human Aging

    Siqi Wang, Danyue Dong ... Zefeng Wang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
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