The SiPIP2;7 aquaporin is a functional CO₂ pore that can be used to improve CO₂ diffusion at the interface between the airspace and leaf mesophyll which limits C₄ photosynthesis.

Electron crystallography and molecular dynamics simulations show that a cholesterol sandwiched in between two neighboring aquaporin-0 tetramers stabilizes the association between the tetramers and thus promotes array formation.

Mice with aquaporin-4 channel deletion exhibit larger interstitial spaces, brain volume and water content, alongside reduced CSF space volume, which may increased resistance towards brain fluid efflux and suppress glymphatic flow.

An international collaboration between five independent research groups replicates findings confirming the importance of aquaporin-4 in glymphatic solute transport using five different mouse knockout lines.

The water channel AQP4 contributes to a tonic water outflow from brain astrocytes, thereby modulating their volume dynamics and the ambient water homeostasis.

Study of TbAQP2 adaptations and substrate interactions shows how this aquaglyceroporin enables cellular entry of large antimicrobial agents in Trypanosoma brucei.

Solute movement in brain extracellular space is determined by solute diffusion, and does not depend on convection or aquaporin-4 expression as predicted by the glymphatic mechanism.

Chemical ablation of olfactory sensory neurons blocks cerebrospinal fluid outflow into the nasal epithelium, leading to alterations of cerebrospinal fluid dynamics.

CTFFIND5 estimates the thickness and tilt of cryogenic electron microscopy samples directly from the power spectrum of a single exposure.

Analysis of a mouse model of megalencephalic leukoencephalopathy with subcortical cysts (MLC) shows that the astrocyte-specific membrane protein MLC1 sustains the postnatal development of perivascular astrocytic processes and that MLC is a developmental disorder of the gliovascular unit.