1,943 results found
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Cytoskeleton: The mother of all actins?

    Felipe Merino, Stefan Raunser
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    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Crenactin forms actin-like double helical filaments regulated by arcadin-2

    Thierry Izoré et al.
    Close evolutionary relationship between eukaryotic F-actin and crenarchaeal crenactin protein is supported by a near-atomic cryoEM structure of double helical filaments, that are inhibited by arcadin-2 through binding to crenactin's hydrophobic groove.
    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
    1. Computational and Systems Biology
    2. Neuroscience

    Sleep: To rebound or not to rebound

    Bethany A Stahl, Alex C Keene
    Sexual arousal in flies counteracts the effects of sleep deprivation.
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    1. Neuroscience

    Mating Behaviour: To mate or not to mate

    Florencia Campetella, Silke Sachse
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    1. Neuroscience

    Neurophysiology: Serotonin's many meanings elude simple theories

    Peter Dayan, Quentin Huys
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    1. Computational and Systems Biology
    2. Neuroscience

    Connectomes: Mapping the mind of a fly

    Jason Pipkin
    Scientists have created the most detailed map of the fruit fly brain to date, identifying over 25,000 neurons and 20 million synapses.
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    1. Genetics and Genomics

    Point of View: Bioengineering horizon scan 2020

    Luke Kemp et al.
    20 emerging issues in bioengineering that will have profound impacts on society have been identified.
    1. Medicine

    Meta-Research: A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals

    Diana Herrera-Perez et al.
    An analysis of more than 3000 randomized controlled trials published in JAMA, the Lancet and NEJM has identified 396 medical reversals.
  1. Point of View: The future of graduate and postdoctoral training in the biosciences

    Peter Hitchcock et al.
    What can institutions and funding agencies do to address an array of issues facing the biomedical research community in the United States?

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