Rod-shaped bacteria preserve their aspect ratios and surface-to-volume scaling by maintaining a homeostatic balance between the rates of cell elongation and division protein synthesis.

HEC transcription factors control the timing of cell fate transitions in a dynamic stem cell system, allowing plants to adapt their developmental program to diverse environments.

Pre-existing enhancers interpret T cell signaling strength in an analogue manner to direct quantitative changes in gene expression within the context of an overall digital response.

Analysis of aging yeast cells using the in-vivo roGFP2-based probe reveals redox-dependent heterogeneity, reflected in a bi-modal distribution of the oxidation status, differential growth and replication, as well as distinct proteomic and transcriptomic profiles.

MHC class II-mediated self-antigen presentation by lymph node stromal cells controls regulatory T cell homeostasis, thus safeguarding immune tolerance.

Bayesian integration is able to predict placebo treatment outcomes by focusing especially on the influence of the precision of expectations.

A new platform for imaging live Drosophila adults yields vivid movies of the midgut over prolonged time scales, opening the door to the real-time study of organ renewal dynamics in a near-native context.

Mitochondrial calcium influx plays distinct roles in presynapse formation, function and stability in sensory hair cells.

The major protein disulfide isomerase family member, PDIA1, is essential in beta cells of mice fed a high-fat diet to maintain glucose homeostasis, proinsulin maturation and organelle integrity.

ATP enters the endoplasmic reticulum (ER) lumen through an SLC35B1/AXER-dependentCaATiER mechanism, and ATP usage in the ER renders 'anti-Warburg' effect by increasing ATP regeneration from OxPhos while decreasing glycolysis.