268 results found
    1. Neuroscience

    Astrocyte morphology is confined by cortical functional boundaries in mammals ranging from mice to human

    Raya Eilam et al.
    The structural morphology of astrocyte processes is constrained by functional boundaries in the mouse, rat and human cortex.
    1. Cell Biology
    2. Neuroscience

    Astrocytes refine cortical connectivity at dendritic spines

    W Christopher Risher et al.
    Spines with multiple excitatory contacts are potential sites for competition between thalamic and cortical axons, which is regulated by the astrocytes through the secreted synaptogenic protein hevin.
    1. Neuroscience

    Astrocytic modulation of excitatory synaptic signaling in a mouse model of Rett syndrome

    Benjamin Rakela et al.
    Astrocytes impact neuronal signaling in brain dependent on status of the transcriptional repressor, Methyl CpG Binding Protein 2.
    1. Neuroscience

    Neuronal activity determines distinct gliotransmitter release from a single astrocyte

    Ana Covelo, Alfonso Araque
    A single astrocyte can decode neuronal activity and, consequently, release distinct gliotransmitters that differentially regulate neurotransmission at single hippocampal synapses.
    1. Developmental Biology

    Mechanism and consequence of abnormal calcium homeostasis in Rett syndrome astrocytes

    Qiping Dong et al.
    Increased spontaneous calcium activity in Rett syndrome astrocytes is a key cell-autonomous phenotype that affects synaptic function and network activity.
    1. Neuroscience

    Astrocytes release prostaglandin E2 to modify respiratory network activity

    David Forsberg et al.
    Astrocytes modulate neuronal networks during hypercapnia, introducing a novel gliotransmitter pathway where prostaglandin E2 regulates breathing.
    1. Neuroscience

    Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks

    Gertrudis Perea et al.
    Astrocytes decode temporal interneuron activity and transform inhibitory into excitatory signals that impact excitatory synaptic strength and neuronal circuit function.
    1. Neuroscience

    Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization

    Steven A Hill et al.
    Astrocytes modulate synaptic remodeling of developing circuits in a cell type-specific manner, with long lasting deficits in synaptic plasticity.
    1. Neuroscience

    Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP

    Junhua Yang et al.
    Astrocytes regulate the pruning of excitatory synapses during early life through ATP signaling.
    1. Neuroscience

    Acute stress enhances adult rat hippocampal neurogenesis and activation of newborn neurons via secreted astrocytic FGF2

    Elizabeth D Kirby et al.
    Exposing rats to acute stress increased the generation of new neurons in a subregion of the hippocampus, and improved the animals' performance in a memory task two weeks later.

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